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The Kwang-il Lim Lab
Systems and Synthetic Biology Laboratory
Department of Chemical and Biological Engineering
Sookmyung Women's University
Publication
"Artificial Intelligence Enhanced Analysis of Genomic DNA Visualized with Nanoparticle-Tagged Peptides under Electron Microscopy",
Priyannth Ramasami Sundharbaabu, Junhyuck Chang, Yunchul Kim, Youmin Shim, Byoungsang Lee, Chanyoung Noh, Sujung Heo, Seung Seo Lee, Sang-Hee Shim, Kwang-il Lim, Kyubong Jo, Jung Heon Lee.,
Small 2024
"Scanning Electron Microscopy Imaging of Large DNA Molecules Using a Metal-Free Electro-Stain Composed of DNA-Binding Proteins and Synthetic Polymers",
Chanyoung Noh, Yoonjung Kang, Sujung Heo, Taesoo Kim, Hayeon Kim, Junhyuck Chang, Priyannth Ramasami Sundharbaabu,
Sanghee Shim, Kwang-il Lim, Jung Heon Lee, Kyubong Jo.,
Advanced science 2024
"Probe-Free Identification of RNA Virus Variants with Point Mutations by Surface-Enhanced Raman Spectroscopy",
Su-jin Hong, Eungyeong Park, Yooh-ha Jang, Ji-yeon Shim, Yeonju Park, Sila Jin, Shuang Guo, Yeon-ju Kim, Min-jeong Son, Lei Chen, Kwang-il Lim*, and Young Mee Jung.*,
Analytical Chemistry 2022
(Top 10% journal)
"Counting DNA molecules on a microchannel surface for quantitative analysis",
Taesoo Kim, Siwon Kim, Chanyoung Noh, Hyeseung Hwang, Jieun Shin, Nabin Won, Seonghyun Lee, Dogeun Kim, Yoonha Jang, Su-Jin Hong, Jungyul Park, Sung Jae Kim, Seongsoo Jang, Kwang-Il Lim**, Kyubong Jo.*,
Talanta 2022
(Top 15% journal)
"Graphene Oxide-Supported Microwell Grids for Preparing Cryo-EM Samples with Controlled Ice Thickness",
Min-Ho Kang, Junsun Park, Sungsu Kang, Sungho Jeon, Minyoung Lee, Ji-Yeon Shim,
Jeeyoung Lee, Tae Jin Jeon, Min Kyung Ahn, Sung Mi Lee, Ohkyung Kwon, Byung Hyo Kim,
Joel R. Meyerson, Min Jae Lee, Kwang-Il Lim,* Soung-Hun Roh,* Won Chul Lee,*
and Jungwon Park.*,
Advanced materials 2021
(Top 5% journal)
"Engineering Genetic Systems for Treating Mitochondrial Diseases",
Yoon-ha Jang, Sae Ryun Ahn, Ji-yeon Shim and Kwang-il Lim.*,
Pharmaceutics 2021
(Top 10% journal)
"Alteration of gammaretroviral vector integration patterns by insertion of histone and leucine zipper into integrase",
Yeji Yang, Ji-eun Lee, Hye-young Jeong, Ji-yeon Shim, Min-joeng Baek, Min-jeong Son, Yeon-ju Kim, Hohsuk Noh, Kwang-il Lim.*,
Biotechnology and Bioengineering 2020
(Top 30% journal)
"Cellular Response of Ventricular-Subventricular Neural Progenitor/Stem Cells to Neonatal Hypoxic-Ischemic Brain Injury and Their Enhanced Neurogenesis",
Jeong Eun Shin, Haejin Lee, Kwangsoo Jung, Miri Kim, Kyujin Hwang, Jungho Han, Joohee Lim, Il-Sun Kim, Kwang-Il Lim* and Kook In Park.*,
Yonsei Medical Journal 2020
(Top 20% journal)
"Molecular-Level Interactions between Engineered Materials and Cells",
Yoon-ha Jang, Xuelin Jin, Prabakaran Shankar, Jung Heon Lee,* Kyubong Jo* and Kwang-il Lim.*,
International Journal of Molecular Sciences 2019
(Top 20% journal)
"Comparative study on the catalytic activity of Fe-doped ZrO2 nanoparticles without significant toxicity through chemical treatment under various pH conditions",
Hye-in Song, JungA Hong, Hangil Lee* and Kwang-il Lim.*,
Scientific Reports 2019
(Top 20% journal)
"Attomolar detection of virus by liquid coplanar-gate graphene transistor on plastic",
Jin Woo Kim, Seunghyun Kim, Yoon-ha Jang, Kwang-il Lim* and Wi Hyoung Lee.*,
Nanotechnology 2019
(Top 30% journal)
"Nanotopography-based engineering of retroviral DNA integration patterns",
Yoon-ha Jang, Yi-seul Park, Jung-soo Nam, Yeji Yang, Ji-eun Lee, Kwang-hee Lee, Minho Kang, Alex Chialastri, Hohsuk Noh, Jungwon Park, Jin Seok Lee* and Kwang-il Lim.*,
Nanoscale 2019
(Top 20% journal)
"Identification of Newly Emerging Influenza Viruses by Detecting the Virally Infected Cells Based on Surface Enhanced Raman Spectroscopy and Principal Component Analysis",
Jae-young Lim, Jung-soo Nam, Hyunku Shin, Jaena Park, Hye-in Song, Minsung Kang, Kwang-il Lim,* and Yeonho Choi.*,
Analytical Chemistry 2019
(Top 5% journal)
"Shifting Retroviral Vector Integrations Away from Transcriptional Start Sites via DNA-Binding Protein Domain Insertion into Integrase",
Jung-soo Nam, Ji-eun Lee, Kwang-hee Lee, Yeji Yang, Soo-hyun Kim, Gyu-un Bae, Hohsuk Noh and Kwang-il Lim.*,
Molecular Therapy-Methods & Clinical Development 2018
(Top 20% journal)
"Single-molecule DNA visualization using
AT-specific red and non-specific green DNA-binding fluorescent proteins",
Jihyun Park, Seonghyun Lee, Nabin Won, Eunji Shin, Soo-Hyun Kim, Min-Young Chun, Jungyeun Gu, Gun-Young Jung, Kwang-Il Lim* and Kyubong Jo.*,
Analyst 2018
(Top 20% journal)
"Interfacial Polymer Brush Layer for DNA Sensors Based on Graphene Transistors",
Gwang Mo Ku, Jin Woo Kim, Yoon-ha Jang, Seunghyun Kim, Kwang-il Lim, and Wi Hyoung Lee.*,
Fibers and Polymers 2018
(Top 20% journal)
"Recent Advances in Mitochondria-Targeted Gene Delivery",
Yoon-ha Jang and Kwang-il Lim.*,
Molecules 2018
(Top 50% journal)
"Liquid coplanar-gate organic/graphene hybrid electronics for label-free detection of single and double-stranded DNA molecules",
Jin Woo Kima, Yoon-ha Jang, Gwang Mo Kua, Seunghyun Kim, Eunho Lee, Kilwon Cho, Kwang-il Lim,* Wi Hyoung Lee.*,
Organic Electronics 2018
(Top 30% journal)
"Stability of Retroviral Vectors Against Ultracentrifugation Is Determined by the Viral Internal Core and Envelope Proteins Used for Pseudotyping",
Soo-hyun Kim, and Kwang-il Lim.*,
Molecules and Cells 2017
(Top 30% journal)
"Filopodia Formation and Proliferation of Mammalian Cells Are Increased on Closely Packed Silica Nanobeads",
Yoon-ha Jang, Seo Young Yoon, Young-hoo Cho, Dahyun Lee, Jin Seok Lee* and Kwang-il Lim.*,
Bulletin of the Korean Chemical Society 2016
"Reliable RT-qPCR-based titration of retroviral and lentiviral vectors via quantification of residual vector plasmid DNA in samples",
Yoon-ha Jang, Hye-in Song, Yeji Yang, Kwang-il Lim.,
Biotechnology Letters 2016
"Identification of Newly Emerging Influenza Viruses by Surface- Enhanced Raman Spectroscopy",
Jae-young Lim, Jung-soo Nam, Se-eun Yang, Hyunku Shin, Yoon-ha Jang, Gyu-Un Bae, Taewook Kang, Kwang-il Lim, and Yeonho Choi.,
Analytical Chemistry 2015
(Top 5% journal)
"Enhanced cellular secretion of AAV2 by expression of foreign viral envelope proteins",
Melissa Kottermana, James T. Koerbera, Jung-soo Nam, Young-hoo Cho, Seung-hyun Kim, Jae-hyung Jang, Kwang-il Lim.,
Biochemical Engineering Journal 2014
(Top 25% journal)
"Recent advances in developing molecular tools for targeted genome engineering of mammalian cells",
Kwang-il Lim.,
BMB Reports 2014
(Top 35% journal)
"Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling",
Randolph S. Ashton, Anthony Conway, Chinmay Pangarkar, Jamie Bergen, Kwang-Il Lim, Priya Shah, Mina Bissell, and David V. Schaffer.,
Nature Neuroscience 2013
(Top 1% journal)
"Genome Sequence of Vibrio sp. Strain EJY3, an Agarolytic Marine Bacterium Metabolizing 3,6-Anhydro-L-Galactose as a Sole Carbon Source",
Hanseong Roh, Eun Ju Yun, Saeyoung Lee, Hyeok-Jin Ko, Sujin Kim, Byung-Yong Kim, Heesang Song, Kwang-il Lim, Kyoung Heon Kim, and In-Geol Choi.,
Journal of Bacteriology 2012
"Retroviral integration profiles: their determinants and implications for gene therapy",
Kwang-il Lim.,
BMB Reports 2012
(top 35% journal)
"Retroviral Infection of hES Cells Produces Random-like Integration Patterns",
Kwang-il Lim.,
Molecules and Cells 2012
(Top 30% journal)
"Resistive switching memory properties of layer-by-layer assembled enzyme multilayers",
Hyunhee Baek, Chanwoo Lee, Kwang-il Lim and Jinhan Cho.,
Nanotechnology 2011
(Top 35% journal)
"Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration properties",
Kwang-il Lim, Ryan Klimczak, Julie H. Yu, and David V. Schaffer.,
PNAS 2010
(Top 5% journal)
"Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants",
John C. Burnett, Kwang-il Lim, Arash Calafi, John J. Rossi, David V. Schaffer and Adam P. Arkin.,
Journal of Virology 2010
(Top 20% journal)
"Computational Fitness Landscape for All Gene-Order Permutations of an RNA Virus",
Kwang-il Lim, John Yin.,
PLoS Computational Biology 2009
(Top 10% journal)
"Molecular Engineering of Viral Gene Delivery Vehicles",
David V. Schaffer, James T. Koerber and Kwang-il Lim.,
Annual Review of Biomedical Engineering 2009
(Top 1% journal)
"Library Selection Approaches to Engineering Enhanced Retroviral and Lentiviral Vectors",
Kwang-il Lim and David V. Schaffer., Combinatorial Chemistry & High Throughput Screening 2008
"Library Selection and Directed Evolution Approaches to Engineering Targeted Viral Vectors",
Jae-Hyung Jang, Kwang-il Lim, David V. Schaffer.,
Biotechnology and Bioengineering 2007
(Top 15% journal)
"Model-Based Design of Growth-Attenuated Viruses",
Kwang-il Lim, Tobias Lang, Vy Lam, John Yin.,
PLoS Computational Biology 2006
(Top 10% journal)
"Dynamic Tradeoffs in the Raft-Mediated Entry of Human Immunodeficiency Virus Type 1 Into Cells",
Kwang-il Lim, John Yin.,
Biotechnology and Bioengineering 2005
(Top 15% journal)
"Localization of Receptors in Lipid Rafts Can Inhibit Signal Transduction",
Kwang-il Lim, John Yin.,
Biotechnology and Bioengineering 2005
(Top 15% journal)
"Engineering Virus Growth by Gene-order Permutation",
Kwang-il Lim, Vy Lam, Tobias Lang and John Yin.,
PLoS Computational Biology 2005
(Top 10% journal)
"Effects of lipid rafts on dynamics of retroviral entry and trafficking: Quantitative analysis",
Kwang-il Lim, Shakti Narayan, John A.T. Young, John Yin.,
Biotechnology and Bioengineering 2004
(Top 15% journal)
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